Document 3056
 DOCN  M94A3056
 TI    Use of CD4 to predict outcome in HIV emergencies.
 DT    9412
 AU    Chang R; Memorial Hospital, New York, NY 10021.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):163 (abstract no. PB0080). Unique
       Identifier : AIDSLINE ICA10/94369519
 AB    The CD4 count has been used as a marker for progression of HIV and
       incorporated into staging and severity of illness scores for HIV, but
       its usefulness as a prognostic marker in an acute setting has not been
       explored. We investigated the use of CD4 in predicting hospitalization
       in acutely ill HIV patients. A series of 210 visits by 97 HIV patients
       to the emergency department of a tertiary care center was reviewed.
       Using a multivariate model, we analyzed hospitalization as an outcome
       variable as it related to the patients' age, sex, HIV risks, chief
       complaints, acute physiologic derangements, and other relevant clinical
       and laboratory findings (15 variables). We found the CD4 count to be
       independently significant (p = .016) in predicting acute HIV
       hospitalization. Of 210 visits, the mean CD4 of hospitalized patients
       was 71 (range 2-361) compared to the mean CD4 of 123 (range 2-659) for
       discharged patients. Of 12 patients with CD4 greater than 400, none were
       hospitalized. Our preliminary data indicates that the CD4 count is
       independently useful as a prognostic marker for the need for
       hospitalization in acutely ill HIV patients. We suggest that an HIV
       patient's CD4 count be incorporated in the decision making regarding
       disposition in an acute setting.
 DE    Antigens, CD4/*BLOOD  *Emergencies  Human  HIV
       Infections/CLASSIFICATION/DIAGNOSIS/*IMMUNOLOGY  *Leukocyte Count
       *Patient Admission  Prognosis  Risk Factors  T4 Lymphocytes/*IMMUNOLOGY
       MEETING ABSTRACT

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